Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 63,
  • Issue 1,
  • pp. 103-107
  • (2009)

High Axial Resolution Raman Probe made of a Single Hollow Optical Fiber

Not Accessible

Your library or personal account may give you access

Abstract

A ball lens mounted hollow optical fiber Raman probe (BHRP) consisting of a single hollow optical fiber (HOF) and a micro-ball lens was developed for performing a high axial resolution and high-sensitivity remote Raman analysis of biomedical tissues. The total diameter of the probe head is 640 μm. The BHRP is useful in the measurement of thin-layered tissues that are in contact with the probe's surface because the probe has a limited depth-of-field optical property. An optical calculation study suggested that it is possible to vary the probe's working distance by selecting different materials and diameters for the ball lens. Empirical studies revealed that this probe has a higher axial resolution and a higher sensitivity than an HOF Raman probe without the ball lens. The spectrum of a mouse stomach measured with the BHRP had better quality and considerably lower noise than that measured with a conventional Raman microscope. These results strongly suggest that the BHRP can be used effectively in biomedical applications.

PDF Article
More Like This
Raman imaging of carious lesions using a hollow optical fiber probe

Eriko Yokoyama, Satoko Kakino, and Yuji Matsuura
Appl. Opt. 47(23) 4227-4230 (2008)

Fiber-optic Raman probe couples ball lens for depth-selected Raman measurements of epithelial tissue

Jianhua Mo, Wei Zheng, and Zhiwei Huang
Biomed. Opt. Express 1(1) 17-30 (2010)

Raman probe using a single hollow waveguide

Yuichi Komachi, Hidetoshi Sato, Yuji Matsuura, Mitsuno Miyagi, and Hideo Tashiro
Opt. Lett. 30(21) 2942-2944 (2005)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved